🔗 Share this article Patients Discontinuing Slimming Injections Gain Back Weight Far More Rapidly Compared to Those on Conventional Diets Obesity treatment involves long-term strategies. Fresh analysis reveals that individuals who come off popular weight-loss injections like Mounjaro or Wegovy may regain lost weight much more quickly than those who end traditional diet and exercise plans. Findings released in a leading medical journal shows that while obese individuals can lose about a fifth of their total mass while on the medication, the mass comes back at an average rate of nearly a kilo each month after stopping. "People buying these treatments should be cognizant of the risk of fast weight regain when the therapy ends," cautioned expert Dr. Susan Jebb. Such speed of regain means a reversion to original weight in about one and a half years. Comparing Approaches The analysis, which reviewed dozens of trials involving over 9,000 of patients, compared the outcomes of these new drugs with older methods. The team note that individuals who lose weight through dieting usually see a slower creep back—perhaps 0.1 kg a month—once they finish. Explaining the Fast Regain Doctors believe the way of the jabs explains the amplified regain. These medications copy a natural hormone called GLP-1, which moderates feelings of fullness. "Sustained high doses of GLP-1 concentrations far above than the body's typical production could lead to the system to produce less of its endogenous GLP-1, and may also diminish sensitivity to its effects," explained Dr. Adam Collins, a dietetics researcher. "Discontinuation of this hormone supplement leads to appetite is no longer kept in check, making overeating far more likely." A Chronic Condition? The NHS suggest the injections for individuals with weight-linked medical conditions, accompanied by recommended lifestyle changes. A number of clinicians argue that, considering the significant potential of relapse, the treatment might need to be long-term. This opinion is supported by pharmaceutical companies, who note that the results "underscore the persistent character of excess weight," similar to managing conditions like hypertension. User Testimonies Users who have discontinued the medication explain a sudden resurgence of hunger. "It was like something flipping and you become extremely hungry," said a patient. The struggle is worsened if individuals have not developed sustainable dietary or behavioural changes during treatment. Widespread Adoption Survey data show that millions of people in the UK have used these injections in the last 12 months, with demand continuing to grow. Use is greater among females compared to males. The 40s and 50s age group shows the greatest usage rates. A large proportion obtain the medications through private healthcare rather than public health services. Finally, researchers stress that while the jabs are effective agents for weight loss, they are not a permanent solution and lasting health benefits relies on combined behavioural support.
Obesity treatment involves long-term strategies. Fresh analysis reveals that individuals who come off popular weight-loss injections like Mounjaro or Wegovy may regain lost weight much more quickly than those who end traditional diet and exercise plans. Findings released in a leading medical journal shows that while obese individuals can lose about a fifth of their total mass while on the medication, the mass comes back at an average rate of nearly a kilo each month after stopping. "People buying these treatments should be cognizant of the risk of fast weight regain when the therapy ends," cautioned expert Dr. Susan Jebb. Such speed of regain means a reversion to original weight in about one and a half years. Comparing Approaches The analysis, which reviewed dozens of trials involving over 9,000 of patients, compared the outcomes of these new drugs with older methods. The team note that individuals who lose weight through dieting usually see a slower creep back—perhaps 0.1 kg a month—once they finish. Explaining the Fast Regain Doctors believe the way of the jabs explains the amplified regain. These medications copy a natural hormone called GLP-1, which moderates feelings of fullness. "Sustained high doses of GLP-1 concentrations far above than the body's typical production could lead to the system to produce less of its endogenous GLP-1, and may also diminish sensitivity to its effects," explained Dr. Adam Collins, a dietetics researcher. "Discontinuation of this hormone supplement leads to appetite is no longer kept in check, making overeating far more likely." A Chronic Condition? The NHS suggest the injections for individuals with weight-linked medical conditions, accompanied by recommended lifestyle changes. A number of clinicians argue that, considering the significant potential of relapse, the treatment might need to be long-term. This opinion is supported by pharmaceutical companies, who note that the results "underscore the persistent character of excess weight," similar to managing conditions like hypertension. User Testimonies Users who have discontinued the medication explain a sudden resurgence of hunger. "It was like something flipping and you become extremely hungry," said a patient. The struggle is worsened if individuals have not developed sustainable dietary or behavioural changes during treatment. Widespread Adoption Survey data show that millions of people in the UK have used these injections in the last 12 months, with demand continuing to grow. Use is greater among females compared to males. The 40s and 50s age group shows the greatest usage rates. A large proportion obtain the medications through private healthcare rather than public health services. Finally, researchers stress that while the jabs are effective agents for weight loss, they are not a permanent solution and lasting health benefits relies on combined behavioural support.